Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123535 | 0.82 | PARP1 (0.42) | — | |
| SCHEMBL2033187 | 0.78 | ALK (0.46) | ADORA1ADORA3ADORA2ADDAH1TNKS2 | |
| SCHEMBL4354597 | 0.78 | ADORA1 (0.38) | ADORA1ADORA3ADORA2ADDAH1TNKS2 | |
| SCHEMBL5216794 | 0.76 | GAA (0.38) | ADORA1ADORA3ADORA2ADDAH1TNKS2 | |
| SCHEMBL5213565 | 0.72 | — | — | |
| SCHEMBL5674009 | 0.72 | — | — | |
| SCHEMBL811725 | 0.65 | TP53 (0.41) | ADORA1ADORA3ADORA2ADDAH1TNKS2 | |
| SCHEMBL3027900 | 0.64 | GAA (0.38) | ADORA1ADORA3ADORA2ADDAH1TNKS2 | |
| SCHEMBL11078634 | 0.63 | GLA (0.38) | ADORA1ADORA3ADORA2AALK | |
| SCHEMBL4352906 | 0.63 | GLA (0.38) | ADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |