Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033187 | 0.84 | ALK (0.46) | ALKADORA2AADORA1ADORA3CDK1 | |
| SCHEMBL4352906 | 0.81 | GLA (0.38) | GLAPOLBKDM4CADORA2AADORA1 | |
| SCHEMBL7763940 | 0.79 | GLA (0.37) | GLAPOLBKDM4CADORA2AADORA1 | |
| SCHEMBL10802354 | 0.74 | CYP1A2 (0.34) | GLAPOLBKDM4EKMT2ACDK1 | |
| SCHEMBL10802364 | 0.74 | CYP1A2 (0.34) | GLAPOLBKDM4EKMT2ACDK1 | |
| SCHEMBL9308282 | 0.73 | GLA (0.38) | GLAPOLBKDM4CKDM4EKMT2A | |
| SCHEMBL7369422 | 0.73 | HSD17B10 (0.50) | POLBKDM4EMAPK1 | |
| SCHEMBL3703329 | 0.73 | GLA (0.40) | GLAPOLBKDM4CADORA2AADORA1 | |
| SCHEMBL9138920 | 0.72 | ADORA3 (0.33) | GLAPOLBKDM4CADORA2AADORA1 | |
| SCHEMBL3701645 | 0.71 | GLA (0.39) | GLAPOLBKDM4CADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447603-A | ANTI -ASTHMATICS | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0057289-A1 | 1-Substituted-6-n-propyl-8-methylimidazo(1,5-d)-as-triazin-4(3H)-ones | AMERICAN CYANAMID COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |
| US-RE30511-E | ENZYME INHIBITOR, HERBICIDE, CYCLIZATION | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4168964-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4124766-A | INTERMEDIATES FOR PHOSPHODIESTERASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4107308-A | HYPOTENSIVE AGENTS, HERBICIDES, REACTING SODIUM SALT WITH ALLYL OR ALKYL HALIDE, RING CLOSURE | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107307-A | ENZYME INHIBITORS, HERBICIDES, RING CLOSURE | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |