Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207309 | 0.90 | NPC1 (0.55) | HDAC1HDAC2HDAC3NPC1RAB9A | |
| SCHEMBL4218396 | 0.83 | NPC1 (0.68) | HDAC1HDAC2HDAC3NPC1RAB9A | |
| SCHEMBL3811403 | 0.81 | NPC1 (0.68) | HDAC1HDAC2HDAC3NPC1RAB9A | |
| SCHEMBL30207803 | 0.81 | NPC1 (0.68) | NPC1RAB9AMGLLMAOBPLAU | |
| SCHEMBL3782118 | 0.81 | NPC1 (0.68) | NPC1RAB9AMGLLMAOBPLAU | |
| SCHEMBL3793285 | 0.80 | MGLL (0.63) | HDAC1HDAC2HDAC3NPC1RAB9A | |
| SCHEMBL3784629 | 0.80 | HDAC1 (0.72) | HDAC1HDAC2HDAC3NPC1RAB9A | |
| SCHEMBL4201825 | 0.79 | MGLL (0.58) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL14793789 | 0.79 | NPC1 (0.57) | HDAC1HDAC2HDAC3NPC1RAB9A | |
| SCHEMBL3786444 | 0.78 | NPC1 (0.68) | NPC1RAB9AMGLLMAOBPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| US-7067533-B2 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | HDAC1 845/4885HDAC2 626/4885HDAC3 765/4885 |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | NR0B1, NR0B2, NR4A1 | HDAC1 714/4885HDAC2 780/4885HDAC3 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.