Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213218 | 0.78 | SCD (0.46) | SCDRXFP1NR3C1ALDH1A1KDM4E | |
| SCHEMBL5215166 | 0.77 | SCD (0.43) | SCDFAAH | |
| SCHEMBL5212084 | 0.77 | SCD (0.43) | SCD | |
| SCHEMBL2563921 | 0.72 | SCD (0.73) | SCDEPHX2 | |
| SCHEMBL5210608 | 0.71 | SCD (0.49) | SCDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9391111 | 0.70 | ACHE (0.49) | ADAMTS4ADAMTS5MMP2 | |
| SCHEMBL5213811 | 0.70 | SCD (0.76) | SCD | |
| SCHEMBL8148649 | 0.70 | TAAR1 (0.48) | ADAMTS4ADAMTS5MMP2EPHX2 | |
| SCHEMBL20694214 | 0.70 | ADRB1 (0.46) | ADAMTS4ADAMTS5MMP2ALDH1A1 | |
| SCHEMBL16191057 | 0.69 | TAAR1 (0.47) | KMT2AADAMTS4ADAMTS5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |