Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 15/20 | 0.38 |
| ▸ | HTR2A | P28223 | 15/20 | 0.38 |
| ▸ | DRD3 | P35462 | 15/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215166 | 0.78 | SCD (0.43) | SCDDRD2HTR2ADRD3 | |
| SCHEMBL5217243 | 0.77 | SCD (0.48) | SCD | |
| SCHEMBL5213218 | 0.73 | SCD (0.46) | SCDCHRM4DRD2HTR2A | |
| SCHEMBL1475280 | 0.71 | CHRM2 (0.40) | CHRM4DRD2DRD3CHRM2CHRM1 | |
| SCHEMBL1475162 | 0.70 | CHRM4 (0.41) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL1475516 | 0.69 | SLC6A4 (0.47) | CHRM4HTR2AATMNMT1 | |
| SCHEMBL5214241 | 0.66 | SCD (0.45) | SCD | |
| SCHEMBL5213811 | 0.65 | SCD (0.76) | SCD | |
| SCHEMBL5210901 | 0.65 | SCD (0.61) | SCD | |
| SCHEMBL5213158 | 0.64 | SCD (0.45) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | claimed |