Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4465454 | 0.99 | HSD11B1 (0.32) | HSD11B1CCNCCDK8 | |
| SCHEMBL2679800 | 0.86 | CCNC (0.39) | HSD11B1CCNCCDK8 | |
| SCHEMBL2678843 | 0.83 | CCNC (0.42) | HSD11B1CCNCCDK8 | |
| SCHEMBL5219426 | 0.81 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL2678934 | 0.80 | CYP11B1 (0.41) | CCNCCDK8 | |
| Bromide SCHEMBL4460345 | 0.80 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL5222614 | 0.79 | NPC1 (0.38) | HSD11B1 | |
| Bromide SCHEMBL4465616 | 0.78 | NPC1 (0.37) | HSD11B1 | |
| SCHEMBL5223359 | 0.77 | CYP11B1 (0.42) | CCNCCDK8 | |
| SCHEMBL2678187 | 0.77 | NPC1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |