SCHEMBL5217353

SCHEMBL5217353

CCN(CC)OC(=O)CCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 3/20 0.61
KDM2A Q9Y2K7 3/20 0.61
EGLN1 Q9GZT9 2/20 0.61
KDM6B O15054 1/20 0.61
KDM5C P41229 1/20 0.61
LMNA P02545 2/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
SUCNR1 Q9BXA5 1/20 0.41
FFAR3 O14843 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
SLC15A2 Q16348 1/20 0.39
TSHR P16473 6/20 0.37
AKR1B1 P15121 1/20 0.36
KDM7A Q6ZMT4 1/20 0.35
GPR84 Q9NQS5 7/20 0.34
PPARG P37231 6/20 0.34
PPARD Q03181 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28780950 0.85 GPR84 (0.50) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL11344696 0.85 GPR84 (0.50) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL10627980 0.84 GPR84 (0.48) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL28789565 0.82 TSHR (0.59) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL28949052 0.81 DGKA (0.41) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL17686889 0.81 ALDH1A1 (0.52) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL5926969 0.79 KDM6B (0.37) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL4399606 0.79 DGKA (0.45) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL28054434 0.78 KDM6B (0.38) PHF8KDM2AEGLN1KDM6BKDM5C
Hydrochloric Acid SCHEMBL5514211 0.77 KDM6B (0.35) PHF8KDM2AEGLN1KDM6BKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006046114-A2 OSMOTIC DOSAGE FORMS PROVIDING ASCENDING DRUG RELEASE, AND PROCESSES FOR THEIR PREPARATION RANBAXY LABORATORIES LIMITED (IN) 2006-05-04 WO claimed
EP-1622591-A1 BIPHASIC RELEASE OF GLIPIZIDE FROM MONOCOMPARTMENT OSMOTIC DOSAGE FORM RANBAXY LABORATORIES, LTD. (IN) 2006-02-08 EP claimed
US-20050208135-A1 Monocompartment osmotic controlled drug delivery system RANBAXY LABORATORIES LIMITED (IN) 2005-09-22 US claimed
EP-1503740-A1 MONOCOMPARTMENT OSMOTIC CONTROLLED DRUG DELIVERY SYSTEM Ranbaxy Laboratories Limited (IN) 2005-02-09 EP claimed
WO-2004098572-A1 BIPHASIC RELEASE OF GLIPIZIDE FROM MONOCOMPARTMENT OSMOTIC DOSAGE FORM RANBAXY LABORATORIES LIMITED (US) 2004-11-18 WO claimed
WO-2003092660-A1 MONOCOMPARTMENT OSMOTIC CONTROLLED DRUG DELIVERY SYSTEM RANBAXY LABORATORIES LIMITED (US) 2003-11-13 WO claimed
US-10137094-B2 Gastroretentive dosage system and process of preparation thereof SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2018-11-27 US disclosed
CN-106074417-A The pharmaceutical carrier of slow-release 钟术光 2016-11-09 CN disclosed
US-20140271846-A1 GASTRORETENTIVE DOSAGE SYSTEM AND PROCESS OF PREPARATION THEREOF RANBAXY LABORATORIES LIMITED (IN) 2014-09-18 US disclosed
EP-2765998-A1 A GASTRORETENTIVE DOSAGE SYSTEM AND PROCESS OF PREPARATION THEREOF Ranbaxy Laboratories Limited (IN) 2014-08-20 EP disclosed
WO-2013054285-A1 A GASTRORETENTIVE DOSAGE SYSTEM AND PROCESS OF PREPARATION THEREOF RANBAXY LABORATORIES LIMITED (IN) 2013-04-18 WO disclosed
EP-1824491-A1 MONOCOMPARTMENT OSMOTIC-CONTROLLED DELIVERY SYSTEM OF DOXAZOSIN Ranbaxy Laboratories Limited (IN) 2007-08-29 EP disclosed
US-20060233875-A1 Taste masked sumatriptan tablets and processes for their preparation RANBAXY LABORATORIES LIMITED (IN) 2006-10-19 US disclosed
EP-1524978-A2 TASTE MASKED SUMATRIPTAN TABLETS AND PROCESSES FOR THEIR PREPARATION RANBAXY LABORATORIES, LTD. (IN) 2005-04-27 EP disclosed
EP-1503740-A1 MONOCOMPARTMENT OSMOTIC CONTROLLED DRUG DELIVERY SYSTEM Ranbaxy Laboratories Limited (IN) 2005-02-09 EP disclosed
WO-2004098572-A1 BIPHASIC RELEASE OF GLIPIZIDE FROM MONOCOMPARTMENT OSMOTIC DOSAGE FORM RANBAXY LABORATORIES LIMITED (US) 2004-11-18 WO disclosed
WO-2004009085-A2 TASTE MASKED SUMATRIPTAN TABLETS AND PROCESSES FOR THEIR PREPARATION RANBAXY LABORATORIES LIMITED (IN) 2004-01-29 WO disclosed
WO-2003092660-A1 MONOCOMPARTMENT OSMOTIC CONTROLLED DRUG DELIVERY SYSTEM RANBAXY LABORATORIES LIMITED (US) 2003-11-13 WO disclosed
WO-2001091716-A1 PERORAL THERAPEUTIC SYSTEM COMPRISING GLIPIZIDE ADD ADVANCED DRUG DELIVERY TECHNOLOGIES AG (CH) 2001-12-06 WO disclosed
US-4992278-A Cellulose casing, core containing hydrophilic polymeric swelling agent blend of vinyl acetate-vinylpyrrolidone copolymer asnd polyoxyethylene glycol CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed