Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27935163 | 0.91 | — | — | |
| SCHEMBL3820880 | 0.81 | KDM4E (0.35) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6553674 | 0.77 | G6PC1 (0.44) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL25201309 | 0.72 | ADH1A (0.35) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL19227252 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EJAK3 | |
| SCHEMBL20733138 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EJAK3 | |
| SCHEMBL19227318 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EJAK3 | |
| SCHEMBL20733110 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EJAK3 | |
| SCHEMBL182620 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EJAK3 | |
| SCHEMBL15009629 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567496-B1 | PHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2007-04-11 | — | — | EP | claimed |
| EP-0274353-B1 | PROCESS FOR THE PREPARATION OF BENZOIN SULFONATES | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| US-4837350-A | Process for the preparation of benzoin sulfonates | CIBA-GEIGY CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0274353-A1 | Process for the preparation of benzoin sulfonates | CIBA-GEIGY AG (CH) | 1988-07-13 | — | — | EP | disclosed |