Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835417 | 0.85 | MEN1 (0.51) | GUSBMTNR1AMTNR1BGPR84MEN1 | |
| SCHEMBL13846906 | 0.85 | NR4A2 (0.46) | GUSBMTNR1AMTNR1BGPR84MEN1 | |
| SCHEMBL1612837 | 0.83 | GUSB (0.44) | GUSBMTNR1AMTNR1BGPR84MEN1 | |
| SCHEMBL13931374 | 0.83 | GPR84 (0.54) | GUSBMTNR1AMTNR1BGPR84MAPT | |
| SCHEMBL22478760 | 0.82 | MAPT (0.64) | GPR84MEN1MAPTPKMKMT2A | |
| SCHEMBL27836177 | 0.77 | GUSB (0.49) | GUSBMTNR1AMTNR1BGPR84MEN1 | |
| SCHEMBL11893400 | 0.77 | NR4A2 (0.51) | GUSBMTNR1AMTNR1BGPR84NR4A2 | |
| SCHEMBL9235264 | 0.76 | GABRA1 (0.47) | GUSBMTNR1AMTNR1BGPR84MEN1 | |
| SCHEMBL18962253 | 0.74 | MEN1 (0.46) | GUSBMEN1MAPTPKMKMT2A | |
| SCHEMBL8592583 | 0.72 | GUSB (0.63) | GUSBGPR84MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618094-B1 | SUBSTITUTED HETEROARYLS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INST FOR PHARM DISCOVERY INC (US) | 2007-09-05 | — | — | EP | disclosed |