SCHEMBL5218244

SCHEMBL5218244

Cc1ccc(CC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.81
RAB9A P51151 5/20 0.81
L3MBTL1 Q9Y468 3/20 0.81
GSK3B P49841 1/20 0.59
KMT2A Q03164 4/20 0.55
MEN1 O00255 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
MAPT P10636 2/20 0.52
SRD5A2 P31213 3/20 0.50
CTBP2 P56545 1/20 0.50
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19934276 0.92 NPC1 (0.71) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL12137308 0.92 NPC1 (0.71) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL12637601 0.92 NPC1 (0.71) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL28629860 0.92 NPC1 (0.71) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL6224695 0.90 RAB9A (1.00) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL29756305 0.90 NPC1 (0.69) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL4464874 0.90 NPC1 (0.69) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL6199337 0.90 RAB9A (1.00) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL31151831 0.90 NPC1 (0.69) NPC1RAB9AL3MBTL1GSK3BKMT2A
SCHEMBL20017608 0.90 NPC1 (0.69) NPC1RAB9AL3MBTL1GSK3BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113755862-B Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2022-08-19 CN claimed
CN-113755862-A Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2021-12-07 CN claimed
CN-118791344-A Method for synthesizing 1, 2-diaryl ketone by alcohol dehydroxycarbonylation 中国科学院大连化学物理研究所 2024-10-18 CN disclosed
US-11732138-B2 Deep ultraviolet-excitable water-solvated polymeric dyes BECTON, DICKINSON AND COMPANY (US) 2023-08-22 US disclosed
US-20230130025-A1 PHOTORESIST COMPOSITIONS AND METHODS FOR FABRICATING SEMICONDUCTOR DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-04-27 US disclosed
CN-113755862-B Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2022-08-19 CN disclosed
CN-113755862-A Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2021-12-07 CN disclosed
US-20180194899-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-07-12 US disclosed
US-20180148544-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIAL CO., LTD. (TW) 2018-05-31 US disclosed
US-20180148541-A1 POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-05-31 US disclosed
US-20180079962-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2018-03-22 US disclosed
US-20110054050-A1 ION EXCHANGE MEMBRANE HAVING LAMELLAR MORPHOLOGY AND PROCESS OF MAKING THE SAME GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-03-03 US disclosed
US-7888433-B2 Sulfonated-polyperfluoro-cyclobutane-polyphenylene polymers for PEM fuel cell applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-02-15 US disclosed
US-20110009506-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2011-01-13 US disclosed
WO-2009123969-A2 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS (US) 2009-10-08 WO disclosed
US-20090053430-A1 Liquid Crystal Display Device and Manufacturing Method Thereof HITACHI DISPLAYS. LTD. 2009-02-26 US disclosed
US-7205302-B2 Anticoagulants; antilipemic agents; cardiovascular disorders NIPPON SHINYAKU CO., LTD. (JP) 2007-04-17 US disclosed
EP-1400518-B1 HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES NIPPON SHINYAKU CO LTD (JP) 2007-01-17 EP disclosed
US-20040102436-A1 Heterocyclic compound derivatives and medicines NIPPON SHINYAKU CO., LTD. (JP) 2004-05-27 US disclosed
EP-1400518-A1 HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES Nippon Shinyaku Co., Ltd. (JP) 2004-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102436-A1 Heterocyclic compound derivatives and medicines CNR2, CNR1, GPR55 NPC1 1164/4885RAB9A 2545/4885L3MBTL1 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.