Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678092 | 0.97 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL2678739 | 0.94 | CHRNB4 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4POLB | |
| SCHEMBL12934786 | 0.81 | VNN1 (0.33) | — | |
| SCHEMBL1482859 | 0.81 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| Bromide SCHEMBL1482837 | 0.80 | CHRNB2 (0.35) | CHRNB2CHRNA4 | |
| SCHEMBL12756183 | 0.78 | ALOX5AP (0.34) | — | |
| SCHEMBL2678755 | 0.78 | — | — | |
| SCHEMBL11929802 | 0.78 | VNN1 (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Bromide SCHEMBL4469527 | 0.77 | KDM1A (0.40) | — | |
| SCHEMBL4463296 | 0.77 | HSD11B1 (0.40) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | disclosed |