SCHEMBL521958

SCHEMBL521958

O=C(CS)Nc1ccc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
POLB P06746 1/20 1.00
ALDH1A1 P00352 6/20 0.70
KDM4E B2RXH2 3/20 0.70
CYP1A2 P05177 2/20 0.70
CYP2C19 P33261 1/20 0.70
HIF1A Q16665 1/20 0.70
RAB9A P51151 4/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
GAA P10253 1/20 0.66
NPC1 O15118 3/20 0.62
LMNA P02545 3/20 0.62
HPGD P15428 3/20 0.56
HTT P42858 1/20 0.56
USP2 O75604 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26397632 0.95 MAPT (0.90) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL11710601 0.85 MEN1 (0.74) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL11710607 0.85 MAPT (0.74) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL29286771 0.84 MAPT (0.72) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL29728198 0.84 MAPT (0.72) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL1285643 0.84 ALDH1A1 (0.73) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL5398875 0.84 CYP1A2 (0.76) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL29205280 0.84 CYP1A2 (0.76) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL31152634 0.84 ALDH1A1 (0.73) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL1913977 0.84 ALDH1A1 (0.73) MAPTMEN1KMT2AL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12207486-B2 Light-emitting element for restraining degradation of electrical and optical properties SHARP KABUSHIKI KAISHA (JP) 2025-01-21 US claimed
US-20240090251-A1 LIGHT-EMITTING ELEMENT SHARP KABUSHIKI KAISHA (JP) 2024-03-14 US claimed
CN-107402206-B Mercury ion colorimetric sensor and preparation method and application thereof 闽南师范大学 2020-04-07 CN claimed
CN-107402206-A A kind of mercury ion colorimetric sensing device and its preparation method and application 闽南师范大学 2017-11-28 CN claimed
US-8975283-B2 Pharmacologically active compounds containing sulfur JON PTY LIMITED (AU) 2015-03-10 US claimed
EP-2724156-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER AND AUTOIMMUNE DISEASE The Jackson Laboratory (US) 2014-04-30 EP claimed
CN-103765212-A Methods and compositions for treating cancer and autoimmune diseases JACKSON LAB 2014-04-30 CN claimed
US-20130123504-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR JON PTY LIMITED (AU) 2013-05-16 US claimed
US-8362041-B2 Pharmacologically active compounds containing sulfur JON PTY LIMITED (AU) 2013-01-29 US claimed
WO-2013003112-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER AND AUTOIMMUNE DISEASE THE JACKSON LABORATORY (US) 2013-01-03 WO claimed
US-6495247-B1 A COORDINATE BOND BEING A MULTIDENTATE BOND WHERE A MOLECULE BONDS WITH METALLIC ATOM ON SURFACE AND THE METALLIC ATOM IS BETWEEN THE LIGAND ATOMS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-12-17 US claimed
US-20020169309-A1 Mutation detection method GJERDE DOUGLAS T (US) 2002-11-14 US claimed
US-20020164589-A1 Detection of nucleic acid heteroduplex molecules by anion-exchange chromatography ADS BIOTEC INC. 2002-11-07 US claimed
EP-1226275-A2 DETECTION OF NUCLEIC ACID HETERODUPLEX MOLECULES BY ANION-EXCHANGE CHROMATOGRAPHY TRANSGENOMIC, Inc. (US) 2002-07-31 EP claimed
WO-2001027331-A2 DETECTION OF NUCLEIC ACID HETERODUPLEX MOLECULES BY ANION-EXCHANGE CHROMATOGRAPHY TRANSGENOMIC, INC. (US) 2001-04-19 WO claimed
EP-1002137-A1 DENATURING MULTI ION POLYNUCLEOTIDE CHROMATOGRAPHY FOR DETECTING MUTATIONS TRANSGENOMIC, Inc. (US) 2000-05-24 EP claimed
WO-1999007899-A1 DENATURING MULTI ION POLYNUCLEOTIDE CHROMATOGRAPHY FOR DETECTING MUTATIONS TRANSGENOMIC, INC. (US) 1999-02-18 WO claimed
US-5824630-A DETERGENCY BUILDER, INORGAIC PEROXYHYDRATE BLEACHING AGENT, PARAFFIN OIL, NITROGEN CONTAINING CORROSION INHIBIOR COMPOUND, MERCAPTAN CORROSION INHIBITOR THE PROCTER & GAMBLE COMPANY 1998-10-20 US claimed
US-5747438-A STORAGE STABILITY THE PROCTER & GAMBLE COMPANY (US) 1998-05-05 US claimed
US-4320209-A Amide nucleating agents for butene-1 polymer compositions SHELL OIL COMPANY (US) 1982-03-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123504-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR SCLY, STS, SQOR MAPT 4757/4885MEN1 4257/4885KMT2A 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.