Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827955 | 0.87 | NPC1 (0.43) | APOBEC3AKMT2AMEN1CNR1RAB9A | |
| SCHEMBL1831964 | 0.86 | NPC1 (0.45) | APOBEC3AKMT2AMEN1CNR1RAB9A | |
| SCHEMBL31098597 | 0.77 | CNR1 (0.56) | APOBEC3AKMT2AMEN1CNR1HPGD | |
| SCHEMBL13903890 | 0.76 | KMT2A (0.63) | KMT2AMEN1CNR1HPGDRAB9A | |
| SCHEMBL6974227 | 0.75 | NPC1 (0.44) | APOBEC3AKMT2AMEN1HPGDRAB9A | |
| Histidine SCHEMBL6813039 | 0.72 | ALPI (0.43) | APOBEC3AKMT2AMEN1HPGDRAB9A | |
| SCHEMBL6966973 | 0.72 | ROCK2 (0.50) | APOBEC3AKMT2AMEN1HPGDRAB9A | |
| SCHEMBL1003665 | 0.72 | KMT2A (0.83) | KMT2AMEN1HPGDRAB9ANPC1 | |
| SCHEMBL11942319 | 0.72 | KMT2A (0.59) | KMT2AMEN1HPGDRAB9ANPC1 | |
| SCHEMBL180384 | 0.71 | NPC1 (0.73) | KMT2AMEN1HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740549-A2 | NOVEL IMIDAZOLES | Warner-Lambert Company LLC (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105079-A2 | NOVEL IMIDAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |