Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739672 | 0.94 | MTNR1A (0.38) | ALDH1A1KDM4ETP53GAAKMT2A | |
| SCHEMBL5217389 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KDM4EEGFRERBB3TP53 | |
| SCHEMBL5305638 | 0.88 | KDM4E (0.40) | ALDH1A1KDM4EEGFRERBB3TP53 | |
| SCHEMBL5739741 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL5221333 | 0.81 | HPGD (0.36) | ALDH1A1KDM4ETP53GAAKMT2A | |
| SCHEMBL5218597 | 0.81 | HPGD (0.36) | ALDH1A1KDM4ETP53GAAKMT2A | |
| SCHEMBL27648335 | 0.77 | HPGD (0.47) | ALDH1A1KDM4ETP53GAAKMT2A | |
| SCHEMBL5720772 | 0.75 | RAB9A (0.48) | ALDH1A1GAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL5740009 | 0.73 | JAK3 (0.40) | ALDH1A1KDM4ETP53GAAKMT2A | |
| SCHEMBL5217343 | 0.73 | CA12 (0.44) | ALDH1A1KDM4ETP53GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |
| CN-1735592-A | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | GLAXO GROUP LTD (GB) | 2006-02-15 | — | — | CN | disclosed |