SCHEMBL522033

SCHEMBL522033

NC(=O)c1cnn(-c2ccccc2-c2cc(F)c(F)c(F)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BTK Q06187 2/20 0.43
FEN1 P39748 5/20 0.40
ALOX5AP P20292 3/20 0.40
NPC1 O15118 4/20 0.38
RAB9A P51151 3/20 0.38
TGFBR1 P36897 1/20 0.38
HPGDS O60760 1/20 0.38
ALKBH2 Q6NS38 1/20 0.38
EGLN1 Q9GZT9 2/20 0.37
PDE4B Q07343 1/20 0.36
MAP4K4 O95819 1/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CYP11B2 P19099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27835961 0.81 ALKBH2 (0.45) BTKNPC1RAB9ATGFBR1HPGDS
SCHEMBL28484188 0.80 ALOX5AP (0.40) FEN1ALOX5APNPC1RAB9ATGFBR1
SCHEMBL21638790 0.76 SCN9A (0.41) BTKHPGDSALKBH2EGLN1
SCHEMBL31322788 0.73 MAPK14 (0.49) BTKNPC1RAB9ATGFBR1HPGDS
SCHEMBL31013160 0.72 BTK (0.42) BTKHPGDSALKBH2EGLN1MAP4K4
SCHEMBL2729239 0.72 ACKR3 (0.43) BTKNPC1RAB9AHPGDSALKBH2
SCHEMBL21065542 0.72 ALKBH2 (0.37) BTKNPC1RAB9ATGFBR1HPGDS
SCHEMBL1555170 0.69 BCAT2 (0.61) FEN1ALOX5APNPC1RAB9A
SCHEMBL2190049 0.69 ALKBH2 (0.74) NPC1RAB9AHPGDSALKBH2EGLN1
SCHEMBL29435113 0.69 BCAT2 (0.61) FEN1ALOX5APNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101908-A1 MIXTURES FOR FUNGAL CONTROL IN SOYBEANS CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
WO-2026101906-A1 MIXTURES FOR FUNGAL CONTROL IN CORN CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
WO-2026101907-A1 MIXTURES FOR FUNGAL CONTROL IN CEREALS CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
EP-3058822-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING PROTHIOCONAZOLE AND FLUXAPYROXAD FOR CONTROLLING BEET DISEASES Bayer Intellectual Property GmbH (DE) 2016-08-24 EP disclosed
US-20120027741-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2012-02-02 US disclosed
EP-2176229-A1 NOVEL CRYSTALLINE FORM OF 3-(DIFLUORMETHYL)-1-METHYL-N -(3',4',5'-TRIFLUOR[1,1'-BIPHENYL]-2-YL)-1H-PYRAZOL-4-CARBOXAMIDE BASF SE (DE) 2010-04-21 EP disclosed
WO-2009007344-A1 NOVEL CRYSTALLINE FORM OF 3-(DIFLUORMETHYL)-1-METHYL-N -(3',4',5'-TRIFLUOR[1,1'-BIPHENYL]-2-YL)-1H-PYRAZOL-4-CARBOXAMIDE BASF SE (DE) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027741-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 BTK 1574/4885FEN1 2462/4885ALOX5AP 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.