Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.30 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19422050 | 0.78 | HSP90AA1 (0.37) | HSP90AA1P2RX7LMNACTNNB1WNT3A | |
| SCHEMBL14080697 | 0.77 | CA2 (0.47) | HSP90AA1P2RX7CA12CA1CA2 | |
| SCHEMBL29579947 | 0.77 | HSP90AA1 (0.39) | HSP90AA1P2RX7LMNACTNNB1WNT3A | |
| SCHEMBL4066547 | 0.77 | HSP90AA1 (0.39) | HSP90AA1P2RX7 | |
| SCHEMBL27564370 | 0.77 | HSP90AA1 (0.39) | HSP90AA1P2RX7LMNACTNNB1WNT3A | |
| SCHEMBL19296833 | 0.77 | HSP90AA1 (0.35) | HSP90AA1P2RX7LMNAPOLB | |
| Hydrochloric Acid SCHEMBL27855557 | 0.76 | CA2 (0.45) | HSP90AA1P2RX7CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27772824 | 0.76 | HSP90AA1 (0.38) | HSP90AA1P2RX7 | |
| SCHEMBL19304143 | 0.74 | HSP90AA1 (0.33) | HSP90AA1P2RX7 | |
| SCHEMBL19304077 | 0.74 | HSP90AA1 (0.33) | HSP90AA1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839144-B1 | PIPERAZINE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL GMBH (DE) | 2001-09-19 | — | — | EP | claimed |
| CN-119564878-A | Bioactive substance conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119504997-A | Bioactive substance conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119497631-A | Antibody drug conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-119486763-A | Antibody drug conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115279417-B | Bioactive substance conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20170247376-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF RAS | ARAXES PHARMA LLC (US) | 2017-08-31 | — | — | US | disclosed |
| CN-102300458-A | New herbicides | — | 2011-12-28 | — | — | CN | disclosed |
| EP-1648871-B1 | PIPERIDINE OR 8-AZA-BICYCLO 3.2.1 OCT-3-YL DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| US-20070112022-A1 | Piperidine derivatives as ccr5 receptor modulators | ASTRAZENECA AB (SE) | 2007-05-17 | — | — | US | disclosed |
| CN-1188473-A | 4-substituted 5-polycyclylpyrimidine herbicides | DOWELANCO (US) | 1998-07-22 | — | — | CN | disclosed |
| US-5780465-A | 4-substituted 5-polycyclylpyrimidine herbicides | DOW AGROSCIENCES LLC (US) | 1998-07-14 | — | — | US | disclosed |
| US-5776858-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0843666-A1 | 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES | DOWELANCO (US) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997037978-A1 | 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES | DOWELANCO (US) | 1997-10-16 | — | — | WO | disclosed |
| EP-0771797-A1 | 1-Azinyl-tetrazolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5254679-A | Containing a quaternized nitrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |
| US-5049558-A | Quaternized nitrogen-heterocycle substituted | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |
| EP-0164944-B1 | CEPHALOSPORIN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-11 | — | — | EP | disclosed |
| EP-0164944-A1 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247376-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF RAS | KRAS, NRAS, HRAS | HSP90AA1 814/4885P2RX7 4672/4885LMNA 1339/4885 |
| US-20070112022-A1 | Piperidine derivatives as ccr5 receptor modulators | CCR5, CCR2, CCR6 | HSP90AA1 1301/4885P2RX7 83/4885LMNA 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.