Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 11/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937794 | 0.92 | MALT1 (0.58) | MALT1MEN1KMT2ATRPV1 | |
| SCHEMBL3937807 | 0.92 | MALT1 (0.58) | MALT1MEN1KMT2ATRPV1 | |
| SCHEMBL1728915 | 0.84 | KMT2A (0.50) | MALT1MEN1KMT2ATRPV1CYP1A2 | |
| SCHEMBL2421306 | 0.83 | MALT1 (0.70) | MALT1KMT2ATRPV1CYP2C19 | |
| SCHEMBL27643780 | 0.82 | TRPV1 (0.55) | MALT1MEN1KMT2ATRPV1 | |
| SCHEMBL1727561 | 0.82 | KMT2A (0.48) | MALT1MEN1KMT2ATRPV1CYP1A2 | |
| SCHEMBL2425939 | 0.81 | MALT1 (0.64) | MALT1MEN1KMT2ATRPV1 | |
| SCHEMBL17844913 | 0.81 | KMT2A (0.47) | MALT1MEN1KMT2ATRPV1CYP1A2 | |
| SCHEMBL5220690 | 0.81 | KDM4E (0.66) | MALT1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3216080 | 0.81 | TRPV1 (0.69) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |