Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 3/20 | 0.45 |
| ▸ | SKP1 | P63208 | 3/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729840 | 0.90 | KMT2A (0.45) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3269143 | 0.82 | CKS1B (0.42) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5220685 | 0.82 | MALT1 (0.64) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1728915 | 0.82 | KMT2A (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1727773 | 0.81 | P2RX7 (0.54) | KMT2AMALT1CKS1BSKP1SKP2 | |
| SCHEMBL5220690 | 0.81 | KDM4E (0.66) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1730153 | 0.80 | CHRM4 (0.52) | MALT1P2RX7 | |
| SCHEMBL17844913 | 0.79 | KMT2A (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3216080 | 0.79 | TRPV1 (0.69) | TRPV1GAA | |
| SCHEMBL3281568 | 0.78 | ALDH1A1 (0.66) | CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |