Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110161 | 0.83 | KDM4E (0.79) | KDM4ERECQLHSD11B1MALT1ALDH1A1 | |
| SCHEMBL27643840 | 0.83 | KDM4E (0.57) | KDM4ERECQLACKR3HSD11B1MALT1 | |
| SCHEMBL1727869 | 0.82 | KDM4E (0.62) | KDM4ERECQLACKR3HSD11B1MALT1 | |
| SCHEMBL1727561 | 0.81 | KMT2A (0.48) | KDM4ERECQLACKR3MALT1ALDH1A1 | |
| SCHEMBL5220685 | 0.81 | MALT1 (0.64) | MALT1MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1728915 | 0.81 | KMT2A (0.50) | KDM4ERECQLMALT1ALDH1A1MEN1 | |
| SCHEMBL31042527 | 0.80 | DRD4 (0.51) | KDM4EALDH1A1DRD2HTR2AMAPT | |
| SCHEMBL1727887 | 0.80 | KDM4E (0.60) | KDM4ERECQLACKR3HSD11B1MALT1 | |
| SCHEMBL13622633 | 0.80 | KDM4E (0.66) | KDM4ERECQLACKR3HSD11B1MALT1 | |
| SCHEMBL3288507 | 0.80 | KDM4E (0.51) | KDM4ERECQLACKR3HSD11B1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |