Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220685 | 0.84 | MALT1 (0.64) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4879872 | 0.82 | KDM4E (0.60) | KMT2ACYP2C19MALT1ALDH1A1KDM4E | |
| SCHEMBL1727561 | 0.82 | KMT2A (0.48) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1728655 | 0.81 | MALT1 (0.45) | KMT2AMALT1TRPV1ALDH1A1KDM4E | |
| SCHEMBL3216080 | 0.81 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL5220690 | 0.81 | KDM4E (0.66) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17844913 | 0.81 | KMT2A (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4876457 | 0.80 | MALT1 (0.60) | KMT2AMEN1MALT1KDM4ERECQL | |
| SCHEMBL3265621 | 0.80 | MALT1 (0.43) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3281568 | 0.80 | ALDH1A1 (0.66) | CYP1A2CYP2C9CYP2C19ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |