Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 10/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1087550 | 0.98 | TACR1 (0.43) | TACR1FKBP4MMP3MMP1TRPV1 | |
| SCHEMBL1087636 | 0.90 | TACR1 (0.42) | TACR1FKBP4MMP3MMP1TRPV1 | |
| SCHEMBL410223 | 0.90 | FKBP4 (0.54) | TACR1FKBP4 | |
| SCHEMBL3244930 | 0.89 | ELANE (0.43) | TACR1FKBP4TRPV1MMP2ELANE | |
| SCHEMBL7048929 | 0.88 | TACR1 (0.51) | TACR1FKBP4MMP3MMP1PSMB9 | |
| SCHEMBL3242151 | 0.86 | OPRM1 (0.40) | TACR1FKBP4MMP3MMP1HDAC3 | |
| Dimethyl Sulfoxide SCHEMBL15323267 | 0.86 | TACR1 (0.43) | TACR1FKBP4MMP3MMP1TRPV1 | |
| SCHEMBL5501048 | 0.84 | TACR1 (0.47) | TACR1FKBP4MMP3MMP1TRPV1 | |
| SCHEMBL5833504 | 0.84 | TACR1 (0.53) | TACR1FKBP4 | |
| SCHEMBL14050092 | 0.84 | FKBP4 (0.57) | TACR1FKBP4MMP3MMP1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137118-A1 | Biologically active protein folding intermediates | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2002-09-26 | — | — | US | claimed |
| US-9862956-B2 | Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi | DANISCO US INC. (US) | 2018-01-09 | — | — | US | disclosed |
| US-9644194-B2 | Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 and uses thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2017-05-09 | — | — | US | disclosed |
| US-9574185-B2 | Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 and uses thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2017-02-21 | — | — | US | disclosed |
| US-20170037417-A9 | EXPRESSION AND HIGH-THROUGHPUT SCREENING OF COMPLEX EXPRESSED DNA LIBRARIES IN FILAMENTOUS FUNGI | DYADIC INTERNATIONAL, INC. (US) | 2017-02-09 | — | — | US | disclosed |
| US-20150211013-A1 | EXPRESSION AND HIGH-THROUGHPUT SCREENING OF COMPLEX EXPRESSED DNA LIBRARIES IN FILAMENTOUS FUNGI | DYADIC INTERNATIONAL, INC. (US) | 2015-07-30 | — | — | US | disclosed |
| US-8785142-B2 | Test arrangement | Sigl, Eva (AT) | 2014-07-22 | — | — | US | disclosed |
| US-8680252-B2 | Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi | DYADIC INTERNATIONAL (USA), INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20140032186-A1 | SYSTEMS AND METHODS FOR ANTIBODY ENGINEERING | DNA TWOPOINTO, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-8635029-B2 | Systems and methods for biopolymer engineering | DNA TWOPOINTO, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| WO-2004029202-A2 | MICROBIAL TRYPSIN VARIANTS HAVING CHYMOTRYPSIN ACTIVITY AND NUCLEIC ACIDS ENCODING SAME | NOVOZYMES BIOTECH, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| EP-0765117-B1 | BIOLOGICAL CONTROL OF INSECTS | UNIV TROBE (AU) | 2004-02-18 | — | — | EP | disclosed |
| US-20020137118-A1 | Biologically active protein folding intermediates | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2002-09-26 | — | — | US | disclosed |
| CN-1074900-C | Biological control of insects | UNIV TROBE (AU) | 2001-11-21 | — | — | CN | disclosed |
| US-5985273-A | AMINOPEPTIDASE INHIBITORS OR METALLOPEPTIDASE INHIBITORS AND FURTHER COMPRISE A NON-STRONGLY-CHELATING PEPTIDASE INHIBITOR. | REED BENJAMIN J (AU) | 1999-11-16 | — | — | US | disclosed |
| EP-0765117-A4 | BIOLOGICAL CONTROL OF INSECTS | UNIV TROBE (AU) | 1998-12-02 | — | — | EP | disclosed |
| CN-1158551-A | Biological control of insects | UNIV TROBE (AU) | 1997-09-03 | — | — | CN | disclosed |
| EP-0765117-A1 | BIOLOGICAL CONTROL OF INSECTS | LA TROBE UNIVERSITY (AU) | 1997-04-02 | — | — | EP | disclosed |
| WO-1996019501-A1 | MODULATORS OF BONE CELL FUNCTION AND USES THEREOF | OSTEOSA INC. (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1995035031-A1 | BIOLOGICAL CONTROL OF INSECTS | LA TROBE UNIVERSITY (AU) | 1995-12-28 | — | — | WO | disclosed |