Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 8/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL15323267 | 0.91 | TACR1 (0.43) | TACR1FKBP4MMP3MMP1KMT2A | |
| SCHEMBL3667052 | 0.89 | FKBP4 (0.58) | TACR1FKBP4KMT2A | |
| SCHEMBL5501196 | 0.88 | TACR1 (0.44) | TACR1FKBP4TRPV1MMP2LMNA | |
| SCHEMBL8010107 | 0.88 | FKBP4 (0.46) | TACR1FKBP4KMT2ATRPV1MMP2 | |
| SCHEMBL7746384 | 0.87 | KMT2A (0.58) | TACR1FKBP4KMT2APSMB9 | |
| SCHEMBL28348611 | 0.86 | FKBP4 (0.47) | TACR1FKBP4MMP3MMP1KMT2A | |
| SCHEMBL28348608 | 0.86 | FKBP4 (0.47) | TACR1FKBP4MMP3MMP1KMT2A | |
| SCHEMBL3396899 | 0.86 | ELANE (0.48) | TACR1FKBP4TRPV1MMP2LMNA | |
| SCHEMBL1257864 | 0.86 | LMNA (0.53) | TACR1KMT2ATRPV1MMP2LMNA | |
| SCHEMBL7076149 | 0.85 | FKBP4 (0.56) | TACR1FKBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620553-A4 | INSECT CHYMOTRYPSIN AND INHIBITORS THEREOF | HEXIMA LTD (AU) | 2007-01-03 | — | — | EP | disclosed |
| EP-1620553-A1 | INSECT CHYMOTRYPSIN AND INHIBITORS THEREOF | Hexima Ltd. (AU) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005012877-A2 | SYSTEMS AND METHODS FOR ANTIBODY ENGINEERING | DNA TWOPOINTO INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| WO-2004094630-A1 | INSECT CHYMOTRYPSIN AND INHIBITORS THEREOF | HEXIMA LTD (AU) | 2004-11-04 | — | — | WO | disclosed |