Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287874 | 0.92 | TAAR1 (0.41) | KIF11KCNN4TAAR1SMN1; SMN2MEN1 | |
| SCHEMBL5221334 | 0.88 | TAAR1 (0.54) | KIF11KCNN4TAAR1SMN1; SMN2KCNH2 | |
| SCHEMBL11569782 | 0.79 | KIF11 (0.64) | KIF11TAAR1SMN1; SMN2KCNH2 | |
| SCHEMBL17931724 | 0.79 | KCNN4 (0.44) | KIF11KCNN4TAAR1KCNE1KCNQ1 | |
| SCHEMBL8325626 | 0.77 | KCNN4 (0.43) | KIF11KCNN4TAAR1KCNE1KCNQ1 | |
| SCHEMBL19441058 | 0.76 | TAAR1 (0.50) | KIF11KCNN4TAAR1KCNE1KCNQ1 | |
| SCHEMBL5308364 | 0.76 | LOXL2 (0.42) | KIF11KCNN4TAAR1SMN1; SMN2MEN1 | |
| SCHEMBL25039132 | 0.73 | KCNN4 (0.50) | KIF11KCNN4TAAR1KCNE1KCNQ1 | |
| SCHEMBL16500593 | 0.73 | ESR1 (0.60) | KIF11KCNN4TAAR1KCNE1KCNQ1 | |
| SCHEMBL17931719 | 0.73 | ESR1 (0.60) | KIF11KCNN4KCNE1KCNQ1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |
| US-4912119-A | Cardiovascular disorders | HEUMANN PHARMA GMBH & CO. (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0262448-A1 | Imidazolylguanidine derivatives, process for their preparation and medicines containing them | HEUMANN PHARMA GMBH & CO (DE) | 1988-04-06 | — | — | EP | disclosed |