SCHEMBL522162

SCHEMBL522162

N#Cc1cc(Cl)c(Cl)cc1C#N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.48
MAPK1 P28482 2/20 0.47
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
VCAM1 P19320 2/20 0.40
KHK P50053 1/20 0.37
PGK1 P00558 1/20 0.36
GPR35 Q9HC97 1/20 0.36
DYRK1A Q13627 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP11B2 P19099 1/20 0.35
AR P10275 1/20 0.35
AHR P35869 1/20 0.35
CSNK1A1 P48729 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
USP8 P40818 1/20 0.34
USP7 Q93009 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29827885 1.00 TRPV4 (0.48) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL6502273 0.88 TRPV4 (0.50) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL145418 0.87 TRPV4 (0.54) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL769651 0.81 KHK (0.48) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL21917738 0.81 MAPK1 (0.44) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL404475 0.81 GAA (0.46) TRPV4MAPK1VCAM1KHKPGK1
SCHEMBL6402867 0.81 TRPV4 (0.40) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL20241879 0.81 TRPV4 (0.40) TRPV4MAPK1MAOAMAOBVCAM1
SCHEMBL6948318 0.81 TSHR (0.41) TRPV4MAPK1VCAM1PGK1AR
SCHEMBL8462168 0.81 TRPV4 (0.52) TRPV4MAPK1VCAM1KHKCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592220-A Anti-aging and anti-corrosion coating and preparation method thereof 湖北宏诚涂料科技股份有限公司 2025-03-11 CN claimed
CN-119552535-A Universal water-based blue ink and preparation method thereof 河南功能高分子膜材料创新中心有限公司 2025-03-04 CN claimed
CN-119490463-A Beta-triazole derivative and synthetic method and application thereof 华东师范大学 2025-02-21 CN claimed
CN-119390975-A Dispersible covalent triazine skeleton and preparation method and application thereof 人工智能与数字经济广东省实验室(深圳) 2025-02-07 CN claimed
CN-119352188-A Functional fiber spinning preparation method based on macro preparation of organic micro-nano photo-thermal eutectic material 苏州大学 2025-01-24 CN claimed
CN-118308010-B Wear-resistant waterproof epoxy anticorrosive paint and preparation method thereof 西安华盾工业设备有限公司 2024-12-24 CN claimed
CN-118878547-A Amine modified zinc phthalocyanine complex and preparation method and application thereof 华侨大学 2024-11-01 CN claimed
CN-118561858-A High water-solubility phthalocyanine modified by amine oxide group, preparation and application thereof 福州大学 2024-08-30 CN claimed
CN-118531524-A Organic micro-nano crystal-based large-area multicolor fluorescence emitting fiber and preparation method and application thereof 苏州大学 2024-08-23 CN claimed
CN-118308010-A Wear-resistant waterproof epoxy anticorrosive paint and preparation method thereof 广东阳光沃土环保科技有限公司 2024-07-09 CN claimed
CN-116837621-A Preparation process and application of phthalonitrile modified aramid fiber 南通新源特种纤维有限公司 2023-10-03 CN claimed
CN-114797487-B Preparation method of polyimide organic solvent nanofiltration membrane containing spiro bisindane structure 西安交通大学 2023-04-07 CN claimed
CN-114797487-A Preparation method of polyimide organic solvent nanofiltration membrane containing spiro bisindane structure 西安交通大学 2022-07-29 CN claimed
CN-114605245-A Method for preparing aromatic aldehyde 中国科学院大连化学物理研究所 2022-06-10 CN claimed
CN-112409365-B 3-sulfopropane sulfydryl modified phthalocyanine, preparation method thereof and application thereof in pharmaceutical field 福州大学 2021-11-02 CN claimed
CN-112500427-A Detecting Fe3+Fluorescent probe and preparation method and application thereof 烟台大学 2021-03-16 CN claimed
CN-112409365-A 3-sulfopropane sulfydryl modified phthalocyanine, preparation method thereof and application thereof in pharmaceutical field 福州大学 2021-02-26 CN claimed
CN-106046009-A Triphenylamine electron-donating group zinc protoporphyrin, synthesis thereof and application thereof to dye sensitizer 西北师范大学 2016-10-26 CN claimed
CN-120923524-A Hole transport material, preparation method thereof and perovskite solar cell 东莞市竞沃电子科技有限公司 2025-11-11 CN disclosed
EP-0042531-A1 Isoindoline derivatives and their uses as intermediates in the preparation of dyestuffs BAYER AG (DE) 1981-12-30 EP disclosed