Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145418 | 0.94 | TRPV4 (0.54) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL10945357 | 0.91 | TRPV4 (0.52) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL522162 | 0.88 | TRPV4 (0.48) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL29827885 | 0.88 | TRPV4 (0.48) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL25235179 | 0.79 | TRPV4 (0.43) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL10947192 | 0.79 | TRPV4 (0.56) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL2473663 | 0.79 | TSHR (0.52) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL7575800 | 0.79 | ALDH1A1 (0.50) | TRPV4PGK1VCAM1ALDH1A1MAOB | |
| SCHEMBL22560907 | 0.79 | TRPV4 (0.43) | TRPV4PGK1VCAM1MAPK1ALDH1A1 | |
| SCHEMBL7073779 | 0.79 | GAA (0.57) | TRPV4PGK1VCAM1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635486-B1 | Process for the preparation of fluorobenzonitriles | CLARIANT GMBH (DE) | 1998-12-09 | — | — | EP | claimed |
| US-5466859-A | Process for preparing fluorobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | claimed |
| EP-0441004-B1 | Process for preparing aromatic nitriles | ENICHEM SINTESI (IT) | 1995-09-06 | — | — | EP | claimed |
| EP-0635486-A2 | Process for the preparation of fluorobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-25 | — | — | EP | claimed |
| EP-0441004-A1 | Process for preparing aromatic nitriles | ENICHEM SYNTHESIS S.p.A. (IT) | 1991-08-14 | — | — | EP | claimed |
| JP-4321644-A | — | — | None | — | — | JP | disclosed |
| CN-111499540-A | Method for preparing 2,4,6-trichlorobenzonitrile by ammoxidation method, special catalyst and preparation method | 中南民族大学 | 2020-08-07 | — | — | CN | disclosed |
| US-6906006-B1 | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-14 | — | — | US | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-0597360-B1 | Substituted N-phenyl-triazolin (thi)ones, processes and intermediates for their production and their use as herbicides, insecticides and acaricides | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0265854-B2 | Process for preparing fluorobenzaldehydes | CLARIANT GMBH (DE) | 1999-03-24 | — | — | EP | disclosed |
| EP-0635486-B1 | Process for the preparation of fluorobenzonitriles | CLARIANT GMBH (DE) | 1998-12-09 | — | — | EP | disclosed |
| EP-0610733-A1 | 1-Aryltriazolinones and thiones | BAYER AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| EP-0609734-A1 | Substituted triazolinones and their use as herbicides | BAYER AG (DE) | 1994-08-10 | — | — | EP | disclosed |
| EP-0599135-A1 | Substituted triazolinones | BAYER AG (DE) | 1994-06-01 | — | — | EP | disclosed |
| EP-0597360-A1 | Substituted N-phenyl-triazolin (thi)ones, processes and intermediates for their production and their use as herbicides, insecticides and acaricides | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-5227531-A | Process for the preparation of fluorobenzaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| JP-H04321644-A | PRODUCTION OF 2,4,5-TRIFLUOROBENZOIC ACID | ASAHI GLASS CO LTD | 1992-11-11 | — | — | JP | disclosed |
| EP-0441004-A1 | Process for preparing aromatic nitriles | ENICHEM SYNTHESIS S.p.A. (IT) | 1991-08-14 | — | — | EP | disclosed |
| EP-0265854-A1 | Process for preparing fluorobenzaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-04 | — | — | EP | disclosed |