SCHEMBL5221687

SCHEMBL5221687

Cc1cc(F)ccc1C1CCCN(C(=O)OC(C)(C)CNC(=O)OCc2ccccc2)C1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 9/20 0.43
CTNNB1 P35222 9/20 0.43
GPR119 Q8TDV5 1/20 0.41
USP30 Q70CQ3 1/20 0.40
CCNT1 O60563 1/20 0.40
CDK9 P50750 1/20 0.40
PREP P48147 2/20 0.40
KAT7 O95251 1/20 0.39
KAT8 Q9H7Z6 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
RORC P51449 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5225678 0.87 BCL9 (0.44) BCL9CTNNB1PREPITGB3ITGA2B
SCHEMBL7367008 0.80 PREP (0.48) PREPNPSR1
SCHEMBL5226259 0.80 OPRL1 (0.43) BCL9CTNNB1MAPTNPSR1
SCHEMBL7382762 0.79 PREP (0.48) PREPNPSR1
SCHEMBL5227765 0.76 GPR119 (0.47) GPR119USP30RORC
SCHEMBL5226606 0.76 GPR119 (0.47) GPR119USP30RORC
SCHEMBL5221681 0.76 GPR119 (0.47) GPR119USP30RORC
SCHEMBL7012823 0.76 SMN1; SMN2 (0.65) GPR119PREP
SCHEMBL5227764 0.75 MAPT (0.41) ITGB3ITGA2BRORCMAPT
SCHEMBL5226602 0.75 MAPT (0.41) ITGB3ITGA2BRORCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1789389-A1 PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME TANABE SEIYAKU CO., LTD. (JP) 2007-05-30 EP disclosed
WO-2006030984-A1 PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME TANABE SEIYAKU CO., LTD. (JP) 2006-03-23 WO disclosed