Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226602 | 1.00 | MAPT (0.41) | MAPTPKMCHRM3ITGB3ITGA2B | |
| SCHEMBL5221674 | 1.00 | MAPT (0.41) | MAPTPKMCHRM3ITGB3ITGA2B | |
| SCHEMBL5225669 | 0.88 | MAPT (0.48) | MAPTPKMITGB3ITGA2BTACR1 | |
| SCHEMBL5226251 | 0.81 | MAPT (0.41) | MAPTPKMCHRM3TACR1 | |
| SCHEMBL7367007 | 0.81 | ALDH1A1 (0.43) | ITGB3ITGA2BHTR2C | |
| SCHEMBL8036361 | 0.78 | ITGB3 (0.45) | ITGB3ITGA2BHTR2C | |
| SCHEMBL7397160 | 0.75 | ALDH1A1 (0.43) | ITGB3ITGA2BHTR2C | |
| SCHEMBL5221687 | 0.75 | BCL9 (0.43) | MAPTITGB3ITGA2BRORC | |
| SCHEMBL20530504 | 0.72 | TACR1 (0.42) | MAPTPKMTACR1 | |
| SCHEMBL5162250 | 0.71 | REN (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789389-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006030984-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-03-23 | — | — | WO | disclosed |