Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4469519 | 0.99 | ALOX5AP (0.33) | GRM5ALOX5APHCRTR1HCRTR2KDM1A | |
| SCHEMBL5156396 | 0.89 | KDM1A (0.43) | ALOX5APHCRTR1HCRTR2KDM1A | |
| Bromide SCHEMBL4466442 | 0.88 | KDM1A (0.42) | ALOX5APHCRTR1HCRTR2KDM1A | |
| Bromide SCHEMBL4461513 | 0.87 | CHRNA7 (0.39) | ALOX5APKDM1ACCR1CCR5CCR8 | |
| SCHEMBL4463296 | 0.83 | HSD11B1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2678523 | 0.82 | CHRNA7 (0.42) | ALOX5APKDM1ACCR1CCR5CCR8 | |
| Bromide SCHEMBL4471147 | 0.82 | HSD11B1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL5216499 | 0.82 | ALOX5AP (0.38) | ALOX5APHCRTR1HCRTR2 | |
| SCHEMBL1482856 | 0.81 | ALOX5AP (0.42) | ALOX5AP | |
| SCHEMBL5218777 | 0.81 | HPGDS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |