SCHEMBL5221954

SCHEMBL5221954

Fc1ccc(-c2ccc(C34CCCN(CC3)C4)cn2)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL4478970 0.99 NSD2 (0.32) NSD2
SCHEMBL5222614 0.84 NPC1 (0.38)
Bromide SCHEMBL4465616 0.83 NPC1 (0.37)
SCHEMBL2678187 0.81 NPC1 (0.39)
SCHEMBL2677959 0.78 NPC1 (0.41)
SCHEMBL2677924 0.78 KDM1A (0.50)
SCHEMBL5219281 0.77 P2RX7 (0.30)
SCHEMBL2679286 0.77 AKT1 (0.36)
SCHEMBL4463296 0.76 HSD11B1 (0.40)
SCHEMBL2678702 0.76 NPC1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465893-B1 DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2007-02-28 EP claimed