Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5221414 | 0.89 | ALDH1A1 (0.31) | ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5216410 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4804902 | 0.81 | KDM4E (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL5198840 | 0.79 | MAPT (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL5197961 | 0.74 | KDM4E (0.41) | — | |
| Hydrochloric Acid SCHEMBL5220811 | 0.73 | ALDH1A1 (0.31) | ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5226294 | 0.71 | OPRM1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5224085 | 0.71 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL4798212 | 0.71 | KDM4E (0.52) | — | |
| SCHEMBL5195813 | 0.70 | KDM4E (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548006-B1 | Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis | OREAL (FR) | 2007-09-05 | — | — | EP | claimed |