Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182392 | 0.88 | PKM (0.46) | CYP1A2CYP2C19ALDH1A1LMNATSHR | |
| SCHEMBL5182662 | 0.87 | MAPT (0.48) | ALDH1A1LMNAGAATSHRL3MBTL1 | |
| SCHEMBL5183669 | 0.85 | GLA (0.39) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL5184258 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAL3MBTL1POLBMEN1 | |
| SCHEMBL5184126 | 0.81 | ALDH1A1 (0.52) | CYP1A2CYP2C19ALDH1A1LMNATSHR | |
| SCHEMBL5182881 | 0.81 | ALDH1A1 (0.45) | CYP1A2CYP2C19ALDH1A1LMNAGAA | |
| SCHEMBL5183754 | 0.81 | ALDH1A1 (0.45) | CYP1A2CYP2C19ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL5182758 | 0.80 | ALDH1A1 (0.37) | ALDH1A1LMNAL3MBTL1POLBMEN1 | |
| SCHEMBL5183841 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAL3MBTL1POLBMEN1 | |
| SCHEMBL5182777 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1LMNAL3MBTL1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301492-B1 | NOVEL TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE KK (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-6770599-B2 | Tetrazole derivatives | BAYER CROPSCIENCE KK (JP) | 2004-08-03 | — | — | US | disclosed |
| US-20030224943-A1 | Novel tetrazole derivatives | BAYER CROPSCIENCE K. K. (JP) | 2003-12-04 | — | — | US | disclosed |
| EP-1301492-A1 | NOVEL TETRAZOLE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002002536-A1 | NOVEL TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE K.K. (DE) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224943-A1 | Novel tetrazole derivatives | CBR3, CBR1, ECH1 | CYP1A2 220/4885CYP2C19 823/4885ALDH1A1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.