SCHEMBL5222352

SCHEMBL5222352

O=C(CSc1cccc(O)c1)Nc1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.64
MEN1 O00255 4/20 0.64
MAPT P10636 2/20 0.64
POLB P06746 3/20 0.64
PPARG P37231 1/20 0.64
NCOA2 Q15596 1/20 0.64
NCOA1 Q15788 1/20 0.64
NCOA3 Q9Y6Q9 1/20 0.64
USP2 O75604 1/20 0.54
HSD17B10 Q99714 3/20 0.52
LMNA P02545 2/20 0.52
HTT P42858 2/20 0.52
ALDH1A1 P00352 1/20 0.52
RAB9A P51151 4/20 0.51
NPC1 O15118 4/20 0.51
PKM P14618 1/20 0.51
TSHR P16473 1/20 0.50
STAT3 P40763 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5201526 0.89 KMT2A (0.70) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL3627574 0.85 KMT2A (0.68) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL930576 0.84 KMT2A (0.71) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL2339823 0.80 KMT2A (0.74) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL1943219 0.80 KMT2A (0.57) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL4624579 0.79 MEN1 (0.57) KMT2AMEN1MAPTPOLBLMNA
SCHEMBL1944556 0.77 KMT2A (0.51) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL6280624 0.76 KMT2A (0.49) KMT2AMEN1MAPTPOLBPPARG
SCHEMBL9617162 0.75 L3MBTL1 (0.84) KMT2AMEN1MAPTPOLBUSP2
SCHEMBL6796256 0.75 ALDH1A1 (0.78) KMT2AMEN1MAPTPOLBPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-7312176-B2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2007-12-25 US disclosed
EP-1559570-B1 HEAT-SENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2007-08-15 EP disclosed
US-20060125909-A1 Heat-sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2006-06-15 US disclosed
EP-1559570-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2005-08-03 EP disclosed