SCHEMBL5201526

SCHEMBL5201526

O=C(CSc1cccc(O)c1)Nc1cccc(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.70
MAPT P10636 4/20 0.70
MEN1 O00255 3/20 0.70
POLB P06746 4/20 0.61
L3MBTL1 Q9Y468 2/20 0.57
RECQL P46063 1/20 0.57
MAPK1 P28482 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HSD17B10 Q99714 1/20 0.57
PKM P14618 3/20 0.55
NPC1 O15118 2/20 0.55
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 2/20 0.51
CYP1A2 P05177 1/20 0.51
NLRP3 Q96P20 3/20 0.51
PPARG P37231 1/20 0.51
NCOA2 Q15596 1/20 0.51
NCOA1 Q15788 1/20 0.51
NCOA3 Q9Y6Q9 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3627574 0.89 KMT2A (0.68) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL5222352 0.89 KMT2A (0.64) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL4624579 0.81 MEN1 (0.57) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL5232613 0.81 KMT2A (0.58) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL5142374 0.79 ALDH1A1 (0.66) KMT2AMAPTMEN1MAPK1ALDH1A1
SCHEMBL127182 0.78 CA1 (0.61) KMT2AMAPTMEN1MAPK1ALDH1A1
SCHEMBL12127509 0.78 ALDH1A1 (0.71) KMT2AMAPTMEN1L3MBTL1MAPK1
SCHEMBL31570060 0.77 ALDH1A1 (0.68) KMT2AMAPTMEN1POLBMAPK1
SCHEMBL10580750 0.77 ALDH1A1 (0.68) KMT2AMAPTMEN1POLBMAPK1
SCHEMBL18922444 0.77 MEN1 (0.60) KMT2AMAPTMEN1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312176-B2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2007-12-25 US disclosed
EP-1559570-B1 HEAT-SENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2007-08-15 EP disclosed
US-20060125909-A1 Heat-sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2006-06-15 US disclosed
EP-1559570-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2005-08-03 EP disclosed