SCHEMBL5222410

SCHEMBL5222410

NC(=O)Oc1ccc(C[C@H](N)C(=O)OCc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.55
LAP3 P28838 1/20 0.55
SLC15A1 P46059 2/20 0.49
SLC7A5 Q01650 2/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
ALDH1A1 P00352 1/20 0.45
F2 P00734 2/20 0.43
PLAU P00749 2/20 0.43
PLAT P00750 2/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
IDO1 P14902 1/20 0.43
LNPEP Q9UIQ6 1/20 0.42
PLG P00747 1/20 0.42
PARP10 Q53GL7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24942191 0.89 LTA4H (0.55) LTA4HLAP3SLC15A1SLC7A5ALPI
Carbamic Acid SCHEMBL13836019 0.87 SLC7A5 (0.59) LTA4HLAP3SLC15A1SLC7A5ALPI
SCHEMBL3099705 0.87 SLC7A5 (0.63) LTA4HLAP3SLC15A1SLC7A5ALPI
SCHEMBL73708 0.87 SLC7A5 (0.63) LTA4HLAP3SLC15A1SLC7A5ALPI
SCHEMBL73707 0.87 SLC7A5 (0.63) LTA4HLAP3SLC15A1SLC7A5ALPI
SCHEMBL6561218 0.86 LTA4H (0.73) LTA4HLAP3PTGS1PPARGPPARA
SCHEMBL1855604 0.86 LTA4H (0.73) LTA4HLAP3PTGS1PPARGPPARA
SCHEMBL8413771 0.86 LTA4H (0.73) LTA4HLAP3PTGS1PPARGPPARA
Hydrochloric Acid SCHEMBL6364440 0.85 SLC7A5 (0.61) LTA4HLAP3SLC15A1SLC7A5ALPI
Hydrochloric Acid SCHEMBL353729 0.85 SLC7A5 (0.61) LTA4HLAP3SLC15A1SLC7A5ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1575900-A4 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LT (AU) 2007-02-21 EP disclosed
US-20050245432-A1 N-methyl amino acids UBIQUITOUS TECHNOLOGIES PTY. LTD. (AU) 2005-11-03 US disclosed
EP-1575900-A1 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LTD (AU) 2005-09-21 EP disclosed
WO-2004007427-A1 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LTD (AU) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245432-A1 N-methyl amino acids VIP, NPPA, PTMS LTA4H 2999/4885LAP3 272/4885SLC15A1 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.