Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121610 | 0.89 | S1PR1 (0.48) | S1PR3S1PR1S1PR5CHRNB2CHRNA7 | |
| SCHEMBL28131709 | 0.88 | S1PR1 (0.49) | S1PR3S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL5509941 | 0.86 | S1PR1 (0.51) | S1PR3S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL17627001 | 0.86 | S1PR1 (0.51) | S1PR3S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL5196974 | 0.86 | S1PR1 (0.48) | S1PR3S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL7733041 | 0.84 | L3MBTL1 (0.43) | S1PR3S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL7501298 | 0.82 | S1PR1 (0.43) | S1PR3S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL5067770 | 0.80 | DPP4 (0.35) | S1PR3S1PR1S1PR5ALOX5PKM | |
| SCHEMBL6274182 | 0.78 | GNAI3 (0.41) | S1PR3S1PR1S1PR5ALOX5GNAI3 | |
| SCHEMBL22287170 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814893-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |