Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274182 | 0.83 | GNAI3 (0.41) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL28037367 | 0.81 | POLB (0.35) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL21409408 | 0.81 | POLB (0.35) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL3877432 | 0.81 | DPP4 (0.37) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL5500987 | 0.80 | DPP4 (0.33) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL17714549 | 0.80 | DPP7 (0.33) | OPRK1 | |
| SCHEMBL27592594 | 0.80 | CHRM2 (0.42) | ALDH1A1CHRM2CHRM1CHRM3MEN1 | |
| SCHEMBL5222630 | 0.80 | S1PR3 (0.40) | DPP4ALOX5S1PR1S1PR3S1PR5 | |
| SCHEMBL28040142 | 0.79 | THRB (0.35) | DPP4POLBHPGDMAPTCHRM2 | |
| SCHEMBL7733041 | 0.78 | L3MBTL1 (0.43) | DPP4POLBMAPTS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144292-B1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (US) | 2020-08-26 | — | — | EP | disclosed |
| CN-106632918-B | Block copolymer and related photo-corrosion-resisting agent composition and the method for forming electronic device | 罗门哈斯电子材料有限责任公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-106893053-B | Sour unstable hyper branched copolymer and associated photo-corrosion-resisting agent composition and the method for forming electronic device | 陶氏环球技术有限责任公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-104330956-B | The method of photoresist composition, the base material of coating and formation electronic device | 罗门哈斯电子材料有限公司 | 2018-04-10 | — | — | CN | disclosed |
| US-9879008-B2 | 2,3,4,6-tetra-substituted benzene-1,5-diamine derivatives, preparation method therefor and medicinal use thereof | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2018-01-30 | — | — | US | disclosed |
| CN-107129448-A | Light acid produces monomer, includes the photo-corrosion-resisting agent composition of the polymer from its derivative polymer | 罗门哈斯电子材料有限责任公司 | 2017-09-05 | — | — | CN | disclosed |
| CN-106893053-A | The unstable hyper branched copolymer of acid and associated photo-corrosion-resisting agent composition and the method for forming electronic device | 陶氏环球技术有限责任公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-106632918-A | Block copolymer and associated photoresist composition and method of forming an electronic device | 罗门哈斯电子材料有限责任公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3144292-A1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20170057957-A1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. (CN) | 2017-03-02 | — | — | US | disclosed |
| CN-102498439-B | Radiation-sensitive resin composition, method for forming resist pattern, polymer, and polymerizable compound | JSR CORP | 2015-03-11 | — | — | CN | disclosed |
| CN-101466726-B | Azacyclo derivatives of androstanes and androstenes as medicaments for the treatment of cardiovascular disorders | SIGMA TAU IND FARMACEUTI | 2014-09-24 | — | — | CN | disclosed |
| CN-103472674-A | Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound | JSR CORP | 2013-12-25 | — | — | CN | disclosed |
| CN-102498439-A | Radiation-sensitive resin composition, method for forming resist pattern, polymer, and polymerizable compound | JSR CORP | 2012-06-13 | — | — | CN | disclosed |
| CN-101466726-A | Azacyclo derivatives of androstanes and androstenes as medicaments for the treatment of cardiovascular disorders | SIGMA TAU IND FARMACEUTI (IT) | 2009-06-24 | — | — | CN | disclosed |
| EP-1963261-A1 | BIARYL SUBSTITUTED NITROGEN CONTAINING HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | Decode Genetics EHF (IS) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007073407-A1 | BIARYL SUBSTITUTED NITROGEN CONTAINING HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2007-06-28 | — | — | WO | disclosed |
| CN-1922173-A | Indanol Derivatives | SANKYO CO (JP) | 2007-02-28 | — | — | CN | disclosed |
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057957-A1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | CYP4F11, CYP2D6, CYP4B1 | DPP4 243/4885POLB 2478/4885HPGD 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.