Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793918 | 0.81 | CKS1B (0.58) | CKS1BSKP1SKP2PDE10AKCNA3 | |
| SCHEMBL5224077 | 0.80 | CKS1B (0.47) | CKS1BSKP1SKP2CTSKPDE10A | |
| SCHEMBL18759677 | 0.80 | CKS1B (0.53) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL13494033 | 0.80 | RBP4 (0.52) | CKS1BSKP1SKP2RBP4TSHR | |
| SCHEMBL10055230 | 0.78 | CKS1B (0.51) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL16299243 | 0.78 | CKS1B (0.51) | CKS1BSKP1SKP2CTSKPDE10A | |
| SCHEMBL29770982 | 0.76 | CTSK (0.46) | CKS1BSKP1SKP2CTSKPDE10A | |
| SCHEMBL28779259 | 0.76 | CTSK (0.46) | CKS1BSKP1SKP2CTSKPDE10A | |
| SCHEMBL18748413 | 0.76 | CKS1B (0.49) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL5525405 | 0.76 | CKS1B (0.49) | CKS1BSKP1SKP2CTSKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |