Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222872 | 1.00 | HSD17B10 (0.36) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5222867 | 1.00 | HSD17B10 (0.36) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5851474 | 0.83 | SMN1; SMN2 (0.42) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5219064 | 0.83 | HSD17B10 (0.42) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5216170 | 0.82 | HSD17B10 (0.41) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5853141 | 0.80 | CFTR (0.41) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5216498 | 0.78 | BACE1 (0.47) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5223450 | 0.78 | ALDH1A1 (0.46) | LMNAMAPTPOLBALDH1A1GAA | |
| SCHEMBL5221159 | 0.78 | LMNA (0.39) | HSD17B10HPGDLMNATSHRMAPT | |
| SCHEMBL5225688 | 0.77 | KMT2A (0.46) | HPGDLMNATSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |