Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 8/20 | 0.33 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL3361058 | 0.97 | EPHX1 (0.43) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL2958868 | 0.94 | EPHX1 (0.41) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL5551211 | 0.92 | EPHX1 (0.40) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL2285727 | 0.88 | ALDH1A1 (0.41) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL1394197 | 0.87 | EPHX1 (0.38) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL3129636 | 0.86 | EPHX1 (0.56) | EPHX1CES1FAAHCES2MEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1851236 | 0.85 | ALDH1A1 (0.39) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL27910342 | 0.85 | ALDH1A1 (0.39) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL27669034 | 0.85 | ALDH1A1 (0.39) | EPHX1ALDH1A1L3MBTL1CES1FAAH | |
| Trifluoromethanesulfonic Acid SCHEMBL10865456 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435071-B2 | Bryostatin compounds and methods of preparing the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-10-07 | — | — | US | disclosed |
| US-20240116908-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2024-04-11 | — | — | US | disclosed |
| US-11746105-B2 | Bryostatin compounds and methods of preparing the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| US-20210292309-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-09-23 | — | — | US | disclosed |
| US-10947221-B2 | Bryostatin compounds and methods of preparing the same | THE BOARD OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-03-16 | — | — | US | disclosed |
| US-20190292172-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-09-26 | — | — | US | disclosed |
| EP-3523296-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | The Board of Trustees of the Leland Stanford Junior University (US) | 2019-08-14 | — | — | EP | disclosed |
| WO-2018067382-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-04-12 | — | — | WO | disclosed |
| CN-101675031-B | Process for stereoselective preparation of 4-BMA using a chiral auxiliary | DAE WOONG PHARMA | 2013-12-11 | — | — | CN | disclosed |
| CN-101675031-A | Use the chiral auxiliary(reagent) stereoselectivity to prepare the method for 4-BMA | DAE WOONG PHARMA | 2010-03-17 | — | — | CN | disclosed |
| EP-1334092-B1 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | UNIV MONASH (AU) | 2007-05-09 | — | — | EP | disclosed |
| US-7012142-B2 | Process for preparation of bicyclic and polycyclic molecules | MONASH UNIVERSITY (AU) | 2006-03-14 | — | — | US | disclosed |
| EP-1334092-A4 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | UNIV MONASH (AU) | 2004-08-11 | — | — | EP | disclosed |
| US-20040010140-A1 | Process for preparation of bicyclic and polycyclic molecules | MONASH UNIVERSITY (AU) | 2004-01-15 | — | — | US | disclosed |
| EP-1334092-A1 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | Monash University (AU) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002034736-A1 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | MONASH UNIVERSITY (AU) | 2002-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746105-B2 | Bryostatin compounds and methods of preparing the same | PROKR1, PBK, PROKR2 | EPHX1 3372/4885ALDH1A1 4077/4885L3MBTL1 2440/4885 |
| US-10947221-B2 | Bryostatin compounds and methods of preparing the same | PROKR1, PBK, PROKR2 | EPHX1 3372/4885ALDH1A1 4077/4885L3MBTL1 2440/4885 |
| US-20040010140-A1 | Process for preparation of bicyclic and polycyclic molecules | CYP2B6, CYP3A4, NR1H4 | EPHX1 1355/4885ALDH1A1 3426/4885L3MBTL1 4572/4885 |
| US-20210292309-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | PROKR1, PBK, PROKR2 | EPHX1 3372/4885ALDH1A1 4077/4885L3MBTL1 2440/4885 |
| US-20190292172-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | PROKR1, PBK, PROKR2 | EPHX1 3372/4885ALDH1A1 4077/4885L3MBTL1 2440/4885 |
| US-20240116908-A1 | BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME | PROKR1, PBK, PROKR2 | EPHX1 3372/4885ALDH1A1 4077/4885L3MBTL1 2440/4885 |
| US-12435071-B2 | Bryostatin compounds and methods of preparing the same | PROKR1, PBK, PROKR2 | EPHX1 3372/4885ALDH1A1 4077/4885L3MBTL1 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.