Amino(Phenyl)Methylphosphonic Acid

Amino(Phenyl)Methylphosphonic Acid

SCHEMBL5223252

N[C@H](c1ccccc1)P(=O)(O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.60
ACP3 P15309 5/20 0.50
ANPEP P15144 4/20 0.50
LAP3 P28838 3/20 0.50
ERAP1 Q9NZ08 2/20 0.47
ERAP2 Q6P179 1/20 0.47
DPP4 P27487 2/20 0.46
F2 P00734 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amino(Phenyl)Methylphosphonic Acid SCHEMBL233491 1.00 SRC (0.60) SRCACP3ANPEPLAP3ERAP1
Amino(Phenyl)Methylphosphonic Acid SCHEMBL7647462 1.00 SRC (0.60) SRCACP3ANPEPLAP3ERAP1
Amino(Phenyl)Methylphosphonic Acid SCHEMBL5575088 0.98 SRC (0.58) SRCACP3ANPEPLAP3ERAP1
Amino(Phenyl)Methylphosphonic Acid SCHEMBL11121764 0.84 CA2 (0.48) SRCACP3ANPEPLAP3ERAP1
SCHEMBL11034382 0.82 SRC (0.50) SRCACP3ANPEPLAP3DPP4
Amino(Phenyl)Methylphosphonic Acid SCHEMBL30161941 0.81 SRC (0.42) SRCACP3ANPEPLAP3DPP4
SCHEMBL15397888 0.79 ANPEP (0.44) SRCACP3ANPEPLAP3ERAP2
Aminodiphenylmethane SCHEMBL1764332 0.78 SRC (0.56) SRCACP3ANPEPLAP3DPP4
Hydrochloric Acid SCHEMBL5935336 0.77 CA12 (0.44) SRCACP3
SCHEMBL11497064 0.77 CYP1A2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1345918-B1 1,5 BENZOTHIAZEPINES AND THEIR USE AS ANTIHYPERLIPIDEMICS ASTRAZENECA AB (SE) 2007-04-18 EP disclosed
US-7192945-B2 Benzothiazepine derivatives ASTRAZENECA AB (SE) 2007-03-20 US disclosed
US-20040067933-A1 Chemical compounds ELOBIX AB (SE) 2004-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067933-A1 Chemical compounds SLC10A2, SLC10A1, ABCB11 SRC 1541/4885ACP3 1785/4885ANPEP 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.