Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP1 | P63208 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383106 | 0.87 | USP2 (0.56) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL5217212 | 0.83 | NPY5R (0.52) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL17830852 | 0.83 | CKS1B (0.61) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL24736635 | 0.82 | CKS1B (0.47) | CKS1BSKP1SKP2KCNA3SUV39H2 | |
| SCHEMBL16528338 | 0.81 | DDR1 (0.50) | CKS1BSKP1SKP2CTSKSUV39H2 | |
| SCHEMBL16528339 | 0.81 | DDR1 (0.50) | CKS1BSKP1SKP2CTSKSUV39H2 | |
| SCHEMBL3281872 | 0.81 | DRD2 (0.44) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL3282053 | 0.81 | CKS1B (0.45) | CKS1BSKP1SKP2CTSKKCNA3 | |
| SCHEMBL5745920 | 0.81 | CKS1B (0.55) | CKS1BSKP1SKP2SUV39H2BTK | |
| SCHEMBL27451700 | 0.81 | CKS1B (0.47) | CKS1BSKP1SKP2CTSKKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |