SCHEMBL24736635

SCHEMBL24736635

Cc1cc(C(=O)O)cc(-c2ccc(N3CCC(NC(=O)OC(C)(C)C)CC3)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 1/20 0.47
SKP1 P63208 1/20 0.47
SKP2 Q13309 1/20 0.47
GPR119 Q8TDV5 6/20 0.43
USP2 O75604 1/20 0.43
SYK P43405 1/20 0.41
KCNA3 P22001 1/20 0.41
SUV39H2 Q9H5I1 2/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
MET P08581 1/20 0.40
NAMPT P43490 1/20 0.39
KDM1A O60341 1/20 0.39
MAOB P27338 1/20 0.39
USP14 P54578 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
HPGDS O60760 1/20 0.39
BTK Q06187 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24736633 0.91 CKS1B (0.44) CKS1BSKP1SKP2GPR119SYK
SCHEMBL30735885 0.91 CKS1B (0.44) CKS1BSKP1SKP2GPR119SYK
SCHEMBL383106 0.85 USP2 (0.56) CKS1BSKP1SKP2GPR119USP2
SCHEMBL5223324 0.82 CKS1B (0.50) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL24736910 0.80 CKS1B (0.42) CKS1BSKP1SKP2SYKKCNA3
SCHEMBL30116297 0.79 GPR119 (0.47) CKS1BSKP1SKP2GPR119SYK
SCHEMBL17830852 0.79 CKS1B (0.61) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL4580200 0.78 CTSK (0.50) CKS1BSKP1SKP2GPR119USP2
SCHEMBL4580205 0.78 CTSK (0.50) CKS1BSKP1SKP2GPR119USP2
SCHEMBL3769327 0.78 GPR119 (0.62) CKS1BSKP1SKP2GPR119KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240246948-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT HK INNO.N CORPORATION (KR) 2024-07-25 US disclosed
EP-4342882-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT HK inno.N Corporation (KR) 2024-03-27 EP disclosed
CN-117396463-A Benzamide derivative for preventing or treating cancer, method for preparing the same, and pharmaceutical composition containing the same as active ingredient 怡诺安有限公司 2024-01-12 CN disclosed
WO-2022245061-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT 에이치케이이노엔 주식회사 2022-11-24 WO disclosed
WO-2022245061-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT 에이치케이이노엔 주식회사 2022-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246948-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT EGFR, ERBB2, TP53 CKS1B 272/4885SKP1 1133/4885SKP2 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.