SCHEMBL5223360

SCHEMBL5223360

CN(C)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 1/20 0.50
MCL1 Q07820 1/20 0.47
ALDH1A1 P00352 2/20 0.44
NSD2 O96028 1/20 0.44
EGFR P00533 1/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CHEK1 O14757 1/20 0.44
NEK2 P51955 1/20 0.44
LIMK1 P53667 1/20 0.44
DYRK1A Q13627 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
HTR1A P08908 2/20 0.43
HTR7 P34969 2/20 0.43
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5401951 0.83 KDM4E (0.40) SIGMAR1MAPTKDM4EGAAMCL1
SCHEMBL29177776 0.83 SIGMAR1 (0.44) SIGMAR1MAPTKDM4EGAAALDH1A1
SCHEMBL29364795 0.82 SIGMAR1 (0.63) SIGMAR1MAPTKDM4EGAAMCL1
SCHEMBL2349 0.82 SIGMAR1 (0.63) SIGMAR1MAPTKDM4EGAAMCL1
SCHEMBL29555314 0.82 SIGMAR1 (0.63) SIGMAR1MAPTKDM4EGAAMCL1
SCHEMBL27737084 0.82 SIGMAR1 (0.63) SIGMAR1MAPTKDM4EGAAMCL1
SCHEMBL2919461 0.82 MAPT (0.52) MAPTKDM4EGAAMCL1ALDH1A1
Hydrochloric Acid SCHEMBL2866027 0.80 SIGMAR1 (0.61) SIGMAR1MAPTKDM4EGAAMCL1
SCHEMBL2173531 0.80 SIGMAR1 (0.61) SIGMAR1MAPTKDM4EGAAMCL1
Hydrogen Sulfide SCHEMBL3359211 0.80 SIGMAR1 (0.61) SIGMAR1MAPTKDM4EGAAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1709085-B1 SUPPORTED ACTIVATOR FOR POLYMERISATION CATALYST EXXONMOBIL CHEM PATENTS INC (US) 2013-03-20 EP claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
US-12103987-B2 Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2024-10-01 US disclosed
US-20220144978-A1 METHOD FOR PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2022-05-12 US disclosed
EP-3950734-A1 PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2022-02-09 EP disclosed
EP-3353217-A1 POLYMERIZATION PROCESS USING PYRIDYLDIAMIDO COMPOUNDS SUPPORTED ON ORGANOALUMINUM TREATED LAYERED SILICATE SUPPORTS ExxonMobil Chemical Patents Inc. (US) 2018-08-01 EP disclosed
WO-2018124588-A1 ORGANIC LIGHT-EMITTING DEVICE 희성소재(주) 2018-07-05 WO disclosed
US-9994658-B2 Polymerization process using bis phenolate compounds supported on organoaluminum treated layered silicate supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-06-12 US disclosed
US-9994657-B2 Polymerization process using bis phenolate compounds supported on organoaluminum treated layered silicate supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-06-12 US disclosed
US-9982067-B2 Polymerization process using pyridyldiamido compounds supported on organoaluminum treated layered silicate supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-05-29 US disclosed
CN-106661626-A Sequences and their use for detection of listeria monocytogenes 纳幕尔杜邦公司 2017-05-10 CN disclosed
EP-1160261-B1 Olefin polymerization catalyst and method for polymerizing olefin using the same JAPAN POLYCHEM CORP (JP) 2007-06-27 EP disclosed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US disclosed
WO-2007023618-A1 HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-01 WO disclosed
EP-1709085-A2 SUPPORTED ACTIVATOR ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2006-10-11 EP disclosed
WO-2005068515-A2 SUPPORTED ACTIVATOR FOR POLYMERISATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-07-28 WO disclosed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US disclosed
US-6531552-B2 Coordination catalyst on silicate support JAPAN POLYCHEM CORPORATION (JP) 2003-03-11 US disclosed
US-20020004447-A1 Olefin polymerization catalyst and method for polymerizing olefin using the same JAPAN POLYCHEM CORPORATION (JP) 2002-01-10 US disclosed
EP-1160261-A1 Olefin polymerization catalyst and method for polymerizing olefin using the same Japan Polychem Corporation (JP) 2001-12-05 EP disclosed