Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4467488 | 0.99 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL4463636 | 0.79 | — | — | |
| SCHEMBL4463296 | 0.78 | HSD11B1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL5220054 | 0.77 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL5217419 | 0.77 | CYP11B1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL2678934 | 0.77 | CYP11B1 (0.41) | HCRTR1HCRTR2 | |
| Bromide SCHEMBL4471147 | 0.77 | HSD11B1 (0.39) | HCRTR1HCRTR2 | |
| Bromide SCHEMBL4469354 | 0.76 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL5223359 | 0.76 | CYP11B1 (0.42) | — | |
| Bromide SCHEMBL4472191 | 0.76 | CYP11B1 (0.37) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |