Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4472191 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2HCRTR1HCRTR2SMARCA2 | |
| SCHEMBL4442686 | 0.97 | CYP11B1 (0.39) | CYP11B1CYP11B2HCRTR1HCRTR2SMARCA2 | |
| SCHEMBL2823249 | 0.81 | ALDH1A1 (0.39) | SMARCA2PBRM1SMARCA4KDM4EALDH1A1 | |
| SCHEMBL4463296 | 0.80 | HSD11B1 (0.40) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL2819670 | 0.80 | ALDH1A1 (0.38) | SMARCA2PBRM1SMARCA4KDM4EALDH1A1 | |
| SCHEMBL1483321 | 0.80 | HCRTR1 (0.35) | HCRTR1HCRTR2CCNCCDK8 | |
| Bromide SCHEMBL4471147 | 0.79 | HSD11B1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL5223359 | 0.79 | CYP11B1 (0.42) | CYP11B1KDM4EALDH1A1MAPTCCNC | |
| Bromide SCHEMBL4467486 | 0.78 | CYP11B1 (0.41) | CYP11B1KDM4EALDH1A1MAPTCCNC | |
| SCHEMBL5218539 | 0.78 | CYP11B1 (0.36) | CYP11B1CYP11B2SMARCA2PBRM1SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |