Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223626 | 1.00 | MEN1 (0.49) | MEN1KMT2AHPGDMETAP2PLAAT3 | |
| SCHEMBL5219507 | 0.87 | SLC2A1 (0.46) | MEN1KMT2AHPGDPLAAT3PLAAT5 | |
| SCHEMBL5219515 | 0.87 | SLC2A1 (0.46) | MEN1KMT2AHPGDPLAAT3PLAAT5 | |
| SCHEMBL5223464 | 0.87 | ADRB3 (0.41) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5223472 | 0.87 | ADRB3 (0.41) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5219638 | 0.84 | ADRB3 (0.43) | MEN1KMT2AL3MBTL1ADRB3 | |
| SCHEMBL5219646 | 0.84 | ADRB3 (0.43) | MEN1KMT2AL3MBTL1ADRB3 | |
| SCHEMBL5217754 | 0.84 | PLAAT3 (0.43) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5217761 | 0.84 | PLAAT3 (0.43) | MEN1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5223889 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AL3MBTL1ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |