Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606006 | 0.85 | CA1 (0.65) | CA1CA2PLAUPLGPLAT | |
| SCHEMBL30698055 | 0.85 | CA1 (0.65) | CA1CA2PLAUPLGPLAT | |
| SCHEMBL5227376 | 0.84 | PLAU (0.56) | PLAUPLGPLATKDM4ESMN1; SMN2 | |
| SCHEMBL5227115 | 0.82 | CYP19A1 (0.44) | APPPLAUPLGPLATSMN1; SMN2 | |
| SCHEMBL5227109 | 0.82 | PLAU (0.48) | APPHDAC6PLAUPLGPLAT | |
| SCHEMBL497643 | 0.82 | HDAC6 (0.62) | CA1CA2HDAC6PLAUPLG | |
| SCHEMBL13900228 | 0.80 | CYP11B1 (0.69) | CA1CA2PLAUPLGPLAT | |
| SCHEMBL6607611 | 0.80 | CYP11B1 (0.42) | HDAC6PLAUPLGPLATSMN1; SMN2 | |
| SCHEMBL1856468 | 0.78 | KDM4E (0.70) | CA1CA2PLAUPLGPLAT | |
| SCHEMBL29906326 | 0.77 | CA1 (0.50) | APPCA1CA2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394158-B1 | Thiophene derivatives and optical elements using the same | FUJIFILM CORP (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1394158-A1 | Novel compounds and optical elements using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |