Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | PLAU | P00749 | 3/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
| ▸ | PLAT | P00750 | 1/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545959 | 0.96 | KDM4E (0.66) | KDM4ECA1CA2PLAUPLG | |
| SCHEMBL69025 | 0.90 | PTPN11 (0.68) | KDM4ECA1CA2PLAUCYP11B1 | |
| SCHEMBL29365729 | 0.90 | PTPN11 (0.68) | KDM4ECA1CA2PLAUCYP11B1 | |
| SCHEMBL12744132 | 0.90 | KDM4E (0.62) | KDM4ECA1CA2PLAUPLG | |
| SCHEMBL7558803 | 0.90 | CA1 (0.65) | KDM4ECA1CA2PLAUPLG | |
| SCHEMBL8698483 | 0.89 | KDM4E (0.70) | KDM4ECA1CA2PLAUPLG | |
| SCHEMBL8732524 | 0.88 | PTPN11 (0.66) | KDM4ECA1CA2PLAUCYP11B1 | |
| SCHEMBL4940300 | 0.87 | KDM4E (0.55) | KDM4ECA1CA2PLAUPLG | |
| SCHEMBL15897010 | 0.86 | CYP11B1 (0.69) | KDM4ECA1CA2PLAUPLG | |
| SCHEMBL30698055 | 0.86 | CA1 (0.65) | KDM4ECA1CA2PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549598-A4 | NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | CORTICAL PTY LTD (AU) | 2008-01-23 | — | — | EP | claimed |
| US-20060106102-A1 | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) | Morand, Eric | 2006-05-18 | — | — | US | claimed |
| EP-1549598-A1 | NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | Cortical Pty Ltd (AU) | 2005-07-06 | — | — | EP | claimed |
| WO-2003104178-A1 | NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | CORTICAL PTY LTD (AU) | 2003-12-18 | — | — | WO | claimed |
| US-20230400770-A1 | Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| US-20230400770-A1 | Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| WO-2023238515-A1 | COMPOSITION, LIQUID CRYSTAL POLYMER SHEET, LOW DIELECTRIC SUBSTRATE MATERIAL, AND WIRING CIRCUIT BOARD | 日東電工株式会社 | 2023-12-14 | — | — | WO | disclosed |
| EP-4290309-A1 | RESIST UNDERLAYER FILM MATERIAL, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-13 | — | — | EP | disclosed |
| US-11674966-B2 | Kit and method for measuring measurement target substance in biological sample | FUJIFILM CORPORATION (JP) | 2023-06-13 | — | — | US | disclosed |
| CN-115160098-B | Oxygen-containing compound deoxidization methylation method | 中国科学院兰州化学物理研究所 | 2023-06-06 | — | — | CN | disclosed |
| EP-4012500-B1 | RESIST UNDERLAYER FILM MATERIAL, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM | SHINETSU CHEMICAL CO (JP) | 2023-03-01 | — | — | EP | disclosed |
| EP-3923074-B1 | RESIST UNDERLAYER FILM MATERIAL, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM | SHINETSU CHEMICAL CO (JP) | 2023-02-22 | — | — | EP | disclosed |
| US-20060217374-A1 | Fused heterocyclic derivates as ppar modulators | ELI LILLY AND COMPANY | 2006-09-28 | — | — | US | disclosed |
| US-20060106102-A1 | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) | Morand, Eric | 2006-05-18 | — | — | US | disclosed |
| EP-1581521-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| US-6849761-B2 | Substituted naphthoic acid derivatives useful in the treatment of insulin resistance and hyperglycemia | WYETH (US) | 2005-02-01 | — | — | US | disclosed |
| WO-2004063190-A1 | FUSED HETEROCYCLIC DERIVATES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |
| US-20040127570-A1 | Substituted naphthoic acid derivatives useful in the treatment of insulin resistance and hyperglycemia | WYETH (US) | 2004-07-01 | — | — | US | disclosed |
| US-5763641-A | Process for the preparation of aromatic methoxycarboxylic acid methyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | disclosed |
| US-4107329-A | Fluorinated compounds as therapeutics | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11674966-B2 | Kit and method for measuring measurement target substance in biological sample | KIT, TACR2, TACR1 | KDM4E 3800/4885CA1 403/4885CA2 1659/4885 |
| US-20060106102-A1 | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) | MIF, ARG1, MSR1 | KDM4E 3166/4885CA1 2883/4885CA2 3698/4885 |
| US-20060217374-A1 | Fused heterocyclic derivates as ppar modulators | PPARG, PPARA, PPARD | KDM4E 2214/4885CA1 4871/4885CA2 4436/4885 |
| US-20040127570-A1 | Substituted naphthoic acid derivatives useful in the treatment of insulin resistance and hyperglycemia | INSR, GPR119, INSRR | KDM4E 3827/4885CA1 3207/4885CA2 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.