Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 5/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230405 | 0.90 | PTGDR2 (0.37) | PTGDR2MEN1KMT2A | |
| SCHEMBL509028 | 0.85 | PTGDR2 (0.38) | PTGDR2CACNA1GCACNA1BKCNH2PGR | |
| SCHEMBL10285742 | 0.83 | CACNA1G (0.35) | PTGDR2CACNA1GCACNA1BKCNH2 | |
| SCHEMBL5228035 | 0.83 | CACNA1G (0.41) | PTGDR2CACNA1GCACNA1BKCNH2PGR | |
| SCHEMBL5231705 | 0.82 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL5226561 | 0.81 | PTGDR2 (0.35) | PTGDR2KCNH2 | |
| SCHEMBL5226939 | 0.80 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL5226225 | 0.80 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL5228817 | 0.79 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL5233666 | 0.75 | PTGDR2 (0.33) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377556-B1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LTD (GB) | 2007-04-04 | — | — | EP | claimed |