Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226939 | 0.91 | PTGDR2 (0.35) | PTGDR2MAPT | |
| SCHEMBL5226225 | 0.91 | PTGDR2 (0.35) | PTGDR2MAPT | |
| SCHEMBL5228817 | 0.90 | PTGDR2 (0.35) | PTGDR2MAPT | |
| SCHEMBL5233666 | 0.86 | PTGDR2 (0.33) | PTGDR2MAPT | |
| SCHEMBL5231705 | 0.84 | PTGDR2 (0.31) | PTGDR2MAPT | |
| SCHEMBL5226341 | 0.84 | FAAH (0.33) | PTGDR2MAPT | |
| SCHEMBL5230405 | 0.83 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL5224713 | 0.81 | PTGDR2 (0.35) | PTGDR2KCNH2 | |
| SCHEMBL509867 | 0.80 | MAPT (0.40) | PTGDR2MAPTKCNH2 | |
| SCHEMBL509118 | 0.79 | MAPT (0.35) | PTGDR2MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377556-B1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LTD (GB) | 2007-04-04 | — | — | EP | claimed |